| 1. Ronde | 03.07.2022 | Pumas UNAM | - | Club Tijuana | 1:1 | ||||
| 2. Ronde | 10.07.2022 | Club León | - | Pumas UNAM | 3:3 | ||||
| 9. Ronde | 19.08.2022 | Atlético San Luis | - | Pumas UNAM | 3:2 | ||||
| 10. Ronde | 21.08.2022 | Pumas UNAM | - | Santos Laguna | 1:5 | ||||
| 16. Ronde | 25.08.2022 | Pumas UNAM | - | UANL Tigres | 1:1 |  |
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| 12. Ronde | 04.09.2022 | Atlas Guadalajara | - | Pumas UNAM | 0:0 | ||||
| 7. Ronde | 24.09.2022 | Puebla FC | - | Pumas UNAM | 2:1 | |
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| 17. Ronde | 01.10.2022 | FC Juárez | - | Pumas UNAM | 3:1 | |
Mexico