| 12. Ronde | 03.09.2022 | CF Pachuca [U20] | - | Santos Laguna [U20] | 5:1 | ||||
| 13. Ronde | 06.09.2022 | Santos Laguna [U20] | - | Club Necaxa [U20] | 3:2 |  |
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| 14. Ronde | 10.09.2022 | Gallos Blancos [U20] | - | Santos Laguna [U20] | 2:2 | ||||
| 5. Ronde | 14.09.2022 | CF América [U20] | - | Santos Laguna [U20] | 1:0 | ||||
| 15. Ronde | 18.09.2022 | Santos Laguna [U20] | - | FC Juárez [U20] | 3:0 | ||||
| 4. Ronde | 22.09.2022 | Deportivo Toluca [U20] | - | Santos Laguna [U20] | 1:0 | ||||
| 17. Ronde | 02.10.2022 | Santos Laguna [U20] | - | Mazatlán FC [U20] | 2:3 |
Mexico