| 2. Ronde | 10.07.2022 | Cruz Azul | - | CF Pachuca | 1:2 | ||||
| 3. Ronde | 17.07.2022 | Atlas Guadalajara | - | Cruz Azul | 3:2 |  |
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| 4. Ronde | 24.07.2022 | Cruz Azul | - | Puebla FC | 2:2 | ||||
| 5. Ronde | 27.07.2022 | Atlético San Luis | - | Cruz Azul | 0:0 | ||||
| 6. Ronde | 31.07.2022 | Cruz Azul | - | Club Necaxa | 1:0 | ||||
| 7. Ronde | 07.08.2022 | Santos Laguna | - | Cruz Azul | 4:0 | ||||
| 8. Ronde | 15.08.2022 | Cruz Azul | - | Deportivo Toluca | 2:3 | ||||
| 9. Ronde | 18.08.2022 | Cruz Azul | - | Club Tijuana | 1:2 | ||||
| 10. Ronde | 21.08.2022 | CF América | - | Cruz Azul | 7:0 |  |
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| 11. Ronde | 28.08.2022 | Cruz Azul | - | Gallos Blancos | 2:1 |  |
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| 12. Ronde | 03.09.2022 | FC Juárez | - | Cruz Azul | 2:2 | ||||
| 13. Ronde | 07.09.2022 | CF Monterrey | - | Cruz Azul | 3:2 | |
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| 17. Ronde | 02.10.2022 | Cruz Azul | - | Deportivo Guadalajara | 2:1 |
Argentinië