| 4. Ronde | 28.01.2023 | Mazatlán FC [] | - | Deportivo Guadalajara [] | 0:1 | ||||
| 6. Ronde | 11.02.2023 | Deportivo Guadalajara [] | - | Santos Laguna [] | 0:0 | ||||
| 8. Ronde | 24.02.2023 | Deportivo Guadalajara [] | - | Club León [] | 2:1 |  |
|||
| 9. Ronde | 04.03.2023 | Atlas Guadalajara [] | - | Deportivo Guadalajara [] | 1:1 | ||||
| 10. Ronde | 11.03.2023 | CF Monterrey [] | - | Deportivo Guadalajara [] | 3:1 | ||||
| 11. Ronde | 19.03.2023 | Deportivo Guadalajara [] | - | Club Tijuana [] | 1:4 | ||||
| 12. Ronde | 25.03.2023 | Club León [] | - | Deportivo Guadalajara [] | 2:2 | ||||
| 15. Ronde | 15.04.2023 | Santos Laguna [] | - | Deportivo Guadalajara [] | 5:3 | ||||
| 16. Ronde | 22.04.2023 | Deportivo Guadalajara [] | - | UANL Tigres [] | 3:2 |
Mexico