| 3. Ronde | 20.01.2023 | Mazatlán FC [U20] | - | Santos Laguna [U20] | 2:3 | ||||
| 4. Ronde | 26.01.2023 | Atlas Guadalajara [U20] | - | Santos Laguna [U20] | 1:2 | ||||
| 5. Ronde | 04.02.2023 | Santos Laguna [U20] | - | CF América [U20] | 0:1 | ||||
| 6. Ronde | 10.02.2023 | FC Juárez [U20] | - | Santos Laguna [U20] | 1:0 | ||||
| 8. Ronde | 18.02.2023 | Atlético San Luis [U20] | - | Santos Laguna [U20] | 0:1 | ||||
| 12. Ronde | 19.03.2023 | Club León [U20] | - | Santos Laguna [U20] | 1:3 | ||||
| 13. Ronde | 31.03.2023 | Club Necaxa [U20] | - | Santos Laguna [U20] | 0:2 |
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