| 4. Ronde | 31.01.2021 | Club Tijuana [U20] | - | Deportivo Toluca [U20] | 1:2 | ||||
| 6. Ronde | 13.02.2021 | Club Tijuana [U20] | - | Club León [U20] | 1:1 | ||||
| 11. Ronde | 14.03.2021 | Club Tijuana [U20] | - | Santos Laguna [U20] | 3:1 |  |
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| 13. Ronde | 03.04.2021 | Atlas Guadalajara [U20] | - | Club Tijuana [U20] | 0:1 | |
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| 14. Ronde | 12.04.2021 | Club Tijuana [U20] | - | Mazatlán FC [U20] | 1:0 | ||||
| 15. Ronde | 17.04.2021 | Deportivo Guadalajara [U20] | - | Club Tijuana [U20] | 2:1 | ||||
| 16. Ronde | 24.04.2021 | Club Tijuana [U20] | - | Club Necaxa [U20] | 3:1 | ||||
| 17. Ronde | 01.05.2021 | Cruz Azul [U20] | - | Club Tijuana [U20] | 0:1 | |
Mexico