| 2. Ronde | 29.08.2021 | St-Pryvé St-Hilaire [A-jun] | - | Lille OSC [A-jun] | 1:2 | ||||
| 3. Ronde | 05.09.2021 | Lille OSC [A-jun] | - | Évreux FC 27 [A-jun] | 3:2 | ||||
| 4. Ronde | 11.09.2021 | Lille OSC [A-jun] | - | Entente Feignies Aulnoye [A-jun] | 3:1 | ||||
| 6. Ronde | 26.09.2021 | Lille OSC [A-jun] | - | JA Drancy [A-jun] | 0:1 | ||||
| 8. Ronde | 10.10.2021 | Lille OSC [A-jun] | - | Havre AC [A-jun] | 1:1 | ||||
| 11. Ronde | 14.11.2021 | Valenciennes FC [A-jun] | - | Lille OSC [A-jun] | 2:1 | ||||
| 12. Ronde | 20.11.2021 | Lille OSC [A-jun] | - | US Orléans [A-jun] | 1:4 | ||||
| 14. Ronde | 05.12.2021 | Lille OSC [A-jun] | - | St-Pryvé St-Hilaire [A-jun] | 6:0 |  |
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| 20. Ronde | 20.03.2022 | Havre AC [A-jun] | - | Lille OSC [A-jun] | 4:2 | ||||
| 25. Ronde | 01.05.2022 | Lille OSC [A-jun] | - | RC Lens [A-jun] | 2:0 |
Frankrijk