| 6. Ronde | 18.09.2021 | FC Porto [A-jun] | - | Gil Vicente [A-jun] | 1:0 | ||||
| 7. Ronde | 25.09.2021 | Vitória Guimarães [A-jun] | - | FC Porto [A-jun] | 0:2 |  |
|||
| 8. Ronde | 02.10.2021 | FC Porto [A-jun] | - | FC Vizela [A-jun] | 3:0 | |
|||
| 9. Ronde | 16.10.2021 | Paços de Ferreira [A-jun] | - | FC Porto [A-jun] | 2:1 |  |
|||
| 10. Ronde | 23.10.2021 | Leixões SC [A-jun] | - | FC Porto [A-jun] | 1:2 | ||||
| 3. Ronde | 27.10.2021 | Rio Ave FC [A-jun] | - | FC Porto [A-jun] | 1:0 | ||||
| 11. Ronde | 30.10.2021 | FC Porto [A-jun] | - | Sporting Braga [A-jun] | 3:0 | ||||
| 12. Ronde | 07.11.2021 | FC Porto [A-jun] | - | CD Feirense [A-jun] | 4:0 | ||||
| 14. Ronde | 13.11.2021 | FC Porto [A-jun] | - | Rio Ave FC [A-jun] | 4:3 | |
|||
| 13. Ronde | 20.11.2021 | FC Famalicão [A-jun] | - | FC Porto [A-jun] | 0:0 | ||||
| 15. Ronde | 01.12.2021 | CD Tondela [A-jun] | - | FC Porto [A-jun] | 1:1 | |
|
Senegal