| 3. Ronde | 21.01.2022 | Mazatlán FC [U18] | - | Deportivo Toluca [U18] | 0:0 |  |
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| 4. Ronde | 06.02.2022 | UANL Tigres [U18] | - | Mazatlán FC [U18] | 3:3 | ||||
| 5. Ronde | 11.02.2022 | Mazatlán FC [U18] | - | Club Tijuana [U18] | 0:2 | |
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| 2. Ronde | 16.02.2022 | Mazatlán FC [U18] | - | CF América [U18] | 0:3 | |
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| 6. Ronde | 20.02.2022 | Gallos Blancos [U18] | - | Mazatlán FC [U18] | 0:1 | ||||
| 7. Ronde | 24.02.2022 | CF Pachuca [U18] | - | Mazatlán FC [U18] | 3:1 | ||||
| 8. Ronde | 01.03.2022 | Mazatlán FC [U18] | - | Club Necaxa [U18] | 2:0 | ||||
| 10. Ronde | 11.03.2022 | CF Monterrey [U18] | - | Mazatlán FC [U18] | 2:2 | ||||
| 11. Ronde | 18.03.2022 | Mazatlán FC [U18] | - | Club León [U18] | 1:1 |
Mexico