| 3. Ronde | 08.08.2020 | Mazatlán FC | - | Deportivo Toluca | 2:1 | ||||
| 4. Ronde | 12.08.2020 | Club Necaxa | - | Mazatlán FC | 1:0 | ||||
| 5. Ronde | 16.08.2020 | Mazatlán FC | - | Pumas UNAM | 0:0 |  |
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| 6. Ronde | 25.08.2020 | CF Pachuca | - | Mazatlán FC | 4:3 | |
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| 7. Ronde | 29.08.2020 | Mazatlán FC | - | UANL Tigres | 1:1 | ||||
| 8. Ronde | 03.09.2020 | CF América | - | Mazatlán FC | 3:1 | ||||
| 9. Ronde | 10.09.2020 | Mazatlán FC | - | Club Tijuana | 1:0 | |
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| 10. Ronde | 13.09.2020 | Atlas Guadalajara | - | Mazatlán FC | 1:1 | ||||
| 11. Ronde | 19.09.2020 | Mazatlán FC | - | Cruz Azul | 2:3 | ||||
| 13. Ronde | 03.10.2020 | Club León | - | Mazatlán FC | 2:1 | ||||
| 14. Ronde | 17.10.2020 | Mazatlán FC | - | FC Juárez | 3:2 | ||||
| 15. Ronde | 25.10.2020 | Mazatlán FC | - | CF Monterrey | 1:2 | ||||
| 16. Ronde | 30.10.2020 | Atlético San Luis | - | Mazatlán FC | 0:5 | ||||
| 17. Ronde | 09.11.2020 | Santos Laguna | - | Mazatlán FC | 4:0 |
Mexico