| 1. Ronde | 05.07.2022 | CF Pachuca | - | Gallos Blancos | 2:0 | ||||
| 2. Ronde | 10.07.2022 | Cruz Azul | - | CF Pachuca | 1:2 | ||||
| 3. Ronde | 19.07.2022 | CF Pachuca | - | Mazatlán FC | 1:1 |  |
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| 4. Ronde | 25.07.2022 | CF Pachuca | - | Pumas UNAM | 0:0 | ||||
| 5. Ronde | 28.07.2022 | Club Necaxa | - | CF Pachuca | 2:0 | ||||
| 6. Ronde | 31.07.2022 | Deportivo Guadalajara | - | CF Pachuca | 0:0 | |
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| 7. Ronde | 08.08.2022 | CF Pachuca | - | UANL Tigres | 2:0 | ||||
| 9. Ronde | 18.08.2022 | CF Pachuca | - | CF América | 0:3 | ||||
| 10. Ronde | 22.08.2022 | CF Pachuca | - | Club León | 1:0 | ||||
| 16. Ronde | 26.08.2022 | CF Pachuca | - | Atlas Guadalajara | 3:1 | ||||
| 11. Ronde | 28.08.2022 | Deportivo Toluca | - | CF Pachuca | 1:4 | ||||
| 12. Ronde | 04.09.2022 | CF Pachuca | - | Santos Laguna | 2:0 | ||||
| 13. Ronde | 08.09.2022 | Puebla FC | - | CF Pachuca | 2:2 | |
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| 14. Ronde | 12.09.2022 | CF Pachuca | - | Club Tijuana | 6:1 |  |
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| 8. Ronde | 15.09.2022 | FC Juárez | - | CF Pachuca | 2:1 | ||||
| 15. Ronde | 19.09.2022 | Atlético San Luis | - | CF Pachuca | 1:2 | ||||
| 17. Ronde | 02.10.2022 | CF Monterrey | - | CF Pachuca | 0:0 |
Mexico