| 1. Ronde | 07.01.2023 | Santos Laguna [] | - | Atlético San Luis [] | 5:0 | ||||
| 7. Ronde | 18.02.2023 | Club Tijuana [] | - | Santos Laguna [] | 2:0 | ||||
| 8. Ronde | 25.02.2023 | Santos Laguna [] | - | Mazatlán FC [] | 2:0 | ||||
| 9. Ronde | 04.03.2023 | UANL Tigres [] | - | Santos Laguna [] | 3:3 | ||||
| 10. Ronde | 11.03.2023 | Santos Laguna [] | - | Atlas Guadalajara [] | 3:0 | ||||
| 12. Ronde | 25.03.2023 | CF Monterrey [] | - | Santos Laguna [] | 2:1 | ||||
| 14. Ronde | 08.04.2023 | Mazatlán FC [] | - | Santos Laguna [] | 0:1 | ||||
| 15. Ronde | 15.04.2023 | Santos Laguna [] | - | Deportivo Guadalajara [] | 5:3 | ||||
| 16. Ronde | 22.04.2023 | Atlético San Luis [] | - | Santos Laguna [] | 0:1 | ||||
| 17. Ronde | 29.04.2023 | Club León [] | - | Santos Laguna [] | 3:0 |
Mexico