| 2. Ronde | 14.08.2021 | Amora FC [A-jun] | - | Académica de Coimbra [A-jun] | 1:2 | ||||
| 4. Ronde | 28.08.2021 | SL Benfica [A-jun] | - | Académica de Coimbra [A-jun] | 6:1 | ||||
| 3. Ronde | 01.09.2021 | Académica de Coimbra [A-jun] | - | CD Nacional [A-jun] | 2:0 |  |
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| 5. Ronde | 11.09.2021 | Académica de Coimbra [A-jun] | - | Os Belenenses [A-jun] | 1:3 | ||||
| 6. Ronde | 18.09.2021 | UD Vilafranquense [A-jun] | - | Académica de Coimbra [A-jun] | 0:3 | ||||
| 7. Ronde | 25.09.2021 | União Leiria [A-jun] | - | Académica de Coimbra [A-jun] | 2:1 | ||||
| 8. Ronde | 02.10.2021 | Académica de Coimbra [A-jun] | - | SG Sacavenense [A-jun] | 4:1 | ||||
| 10. Ronde | 23.10.2021 | Académica de Coimbra [A-jun] | - | Vitória Setúbal [A-jun] | 1:2 | ||||
| 19. Ronde | 08.01.2022 | SG Sacavenense [A-jun] | - | Académica de Coimbra [A-jun] | 0:0 | ||||
| 14. Ronde | 11.01.2022 | CD Nacional [A-jun] | - | Académica de Coimbra [A-jun] | 3:2 | |
Portugal