| 1. Ronde | 08.01.2021 | Mazatlán FC [U20] | - | Club Necaxa [U20] | 2:0 | ||||
| 3. Ronde | 22.01.2021 | Mazatlán FC [U20] | - | Santos Laguna [U20] | 2:2 | ||||
| 5. Ronde | 07.02.2021 | Deportivo Toluca [U20] | - | Mazatlán FC [U20] | 3:1 | ||||
| 6. Ronde | 12.02.2021 | Mazatlán FC [U20] | - | Atlético San Luis [U20] | 1:0 | ||||
| 7. Ronde | 19.02.2021 | FC Juárez [U20] | - | Mazatlán FC [U20] | 2:2 | ||||
| 9. Ronde | 03.03.2021 | Cruz Azul [U20] | - | Mazatlán FC [U20] | 2:2 | ||||
| 10. Ronde | 06.03.2021 | Mazatlán FC [U20] | - | Deportivo Guadalajara [U20] | 2:1 | ||||
| 11. Ronde | 13.03.2021 | UANL Tigres [U20] | - | Mazatlán FC [U20] | 2:1 | ||||
| 12. Ronde | 19.03.2021 | Mazatlán FC [U20] | - | CF América [U20] | 1:0 | ||||
| 13. Ronde | 02.04.2021 | Puebla FC [U20] | - | Mazatlán FC [U20] | 6:2 | ||||
| 14. Ronde | 12.04.2021 | Club Tijuana [U20] | - | Mazatlán FC [U20] | 1:0 | ||||
| 16. Ronde | 23.04.2021 | Mazatlán FC [U20] | - | Club León [U20] | 1:3 | ||||
| 17. Ronde | 01.05.2021 | CF Monterrey [U20] | - | Mazatlán FC [U20] | 2:0 |
Mexico