| 5. Ronde | 11.09.2001 | Santos Laguna | - | Pumas UNAM | 1:0 | ||||
| 11. Ronde | 29.09.2001 | Santos Laguna | - | Deportivo Guadalajara | 0:1 | ||||
| 12. Ronde | 05.10.2001 | UAG Tecos | - | Santos Laguna | 1:2 | ||||
| 13. Ronde | 13.10.2001 | Puebla FC | - | Santos Laguna | 2:1 |  |
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| 14. Ronde | 19.10.2001 | Santos Laguna | - | Atlante | 2:1 | |
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| 15. Ronde | 27.10.2001 | Monarcas Morelia | - | Santos Laguna | 3:2 | ||||
| 16. Ronde | 03.11.2001 | Santos Laguna | - | CF América | 2:3 | ||||
| 17. Ronde | 10.11.2001 | CF Pachuca | - | Santos Laguna | 2:1 | ||||
| 18. Ronde | 17.11.2001 | Santos Laguna | - | UANL Tigres | 1:2 | |
Mexico