| 2. Ronde | 01.08.2021 | FC Basel 1893 | - | FC Sion | 6:1 |  |
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| 3. Ronde | 07.08.2021 | FC Sion | - | BSC Young Boys | 1:0 | ||||
| 4. Ronde | 21.08.2021 | FC St. Gallen | - | FC Sion | 1:1 | ||||
| 5. Ronde | 28.08.2021 | FC Sion | - | FC Lugano | 3:2 | |
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| 6. Ronde | 12.09.2021 | FC Lausanne-Sport | - | FC Sion | 1:1 | |
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| 7. Ronde | 23.09.2021 | FC Sion | - | FC Luzern | 1:1 | |
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| 9. Ronde | 03.10.2021 | FC Zürich | - | FC Sion | 6:2 | ||||
| 11. Ronde | 24.10.2021 | Servette FC | - | FC Sion | 1:2 | ||||
| 12. Ronde | 31.10.2021 | FC Sion | - | Grasshopper Club Zürich | 1:3 | ||||
| 16. Ronde | 05.12.2021 | FC Lugano | - | FC Sion | 2:0 |
Ivoorkust
