| 1. Ronde | 12.02.2022 | Vitória Guimarães [A-jun] | - | FC Alverca [A-jun] | 2:2 |  |
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| 2. Ronde | 19.02.2022 | Sporting Braga [A-jun] | - | Vitória Guimarães [A-jun] | 3:0 | ||||
| 3. Ronde | 26.02.2022 | Vitória Guimarães [A-jun] | - | FC Porto [A-jun] | 1:2 | ||||
| 4. Ronde | 06.03.2022 | SL Benfica [A-jun] | - | Vitória Guimarães [A-jun] | 4:1 | ||||
| 5. Ronde | 13.03.2022 | Vitória Guimarães [A-jun] | - | Sporting CP [A-jun] | 1:2 |  |
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| 13. Ronde | 21.05.2022 | GD Estoril [A-jun] | - | Vitória Guimarães [A-jun] | 0:4 | ||||
| 14. Ronde | 28.05.2022 | Vitória Guimarães [A-jun] | - | Rio Ave FC [A-jun] | 2:2 |
Portugal