| 1. Ronde | 25.06.2022 | Mazatlán FC [] | - | Club Tijuana [] | 0:3 | ||||
| 2. Ronde | 02.07.2022 | CF Monterrey [] | - | Mazatlán FC [] | 4:1 | ||||
| 3. Ronde | 09.07.2022 | Mazatlán FC [] | - | Atlético San Luis [] | 1:2 | ||||
| 5. Ronde | 23.07.2022 | Santos Laguna [] | - | Mazatlán FC [] | 5:0 | ||||
| 6. Ronde | 30.07.2022 | Mazatlán FC [] | - | Atlas Guadalajara [] | 2:5 |  |
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| 7. Ronde | 06.08.2022 | UANL Tigres [] | - | Mazatlán FC [] | 2:1 | ||||
| 11. Ronde | 03.09.2022 | Mazatlán FC [] | - | Deportivo Guadalajara [] | 2:8 | |
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| 15. Ronde | 01.10.2022 | Mazatlán FC [] | - | Santos Laguna [] | 2:3 | ||||
| 18. Ronde | 22.10.2022 | Mazatlán FC [] | - | CF Monterrey [] | 0:4 |
Mexico