| 1. Ronde | 12.04.2021 | Universidad de Concepción | - | Santiago Morning | 3:3 |  |
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| 3. Ronde | 26.04.2021 | Santiago Morning | - | Santa Cruz | 1:3 | |
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| 4. Ronde | 03.05.2021 | Deportes Copiapó | - | Santiago Morning | 2:2 | ||||
| 5. Ronde | 10.05.2021 | Santiago Morning | - | San Marcos | 3:0 | ||||
| 7. Ronde | 24.05.2021 | Santiago Morning | - | Rangers | 0:0 | ||||
| 17. Ronde | 27.08.2021 | CD Magallanes | - | Santiago Morning | 0:1 | ||||
| 20. Ronde | 17.09.2021 | San Marcos | - | Santiago Morning | 4:0 | ||||
| 21. Ronde | 22.09.2021 | Santiago Morning | - | Cobreloa | 2:1 | |
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| 24. Ronde | 09.10.2021 | Coquimbo Unido | - | Santiago Morning | 2:1 | ||||
| 25. Ronde | 13.10.2021 | Santiago Morning | - | Barnechea | 2:0 | ||||
| 26. Ronde | 21.10.2021 | San Luis | - | Santiago Morning | 2:2 | ||||
| 27. Ronde | 25.10.2021 | Santiago Morning | - | Deportes Iquique | 1:0 | ||||
| 8. Ronde | 09.11.2021 | Fernández Vial | - | Santiago Morning | 0:0 | |
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