| 1. Ronde | 12.01.2021 | CF Pachuca | - | FC Juárez | 1:1 |  |
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| 2. Ronde | 16.01.2021 | FC Juárez | - | Club Tijuana | 0:0 | ||||
| 3. Ronde | 27.01.2021 | CF América | - | FC Juárez | 2:0 | ||||
| 4. Ronde | 31.01.2021 | Deportivo Guadalajara | - | FC Juárez | 1:2 | ||||
| 6. Ronde | 13.02.2021 | Puebla FC | - | FC Juárez | 4:0 | ||||
| 7. Ronde | 20.02.2021 | FC Juárez | - | Mazatlán FC | 1:0 | ||||
| 8. Ronde | 01.03.2021 | Santos Laguna | - | FC Juárez | 3:2 | ||||
| 9. Ronde | 04.03.2021 | FC Juárez | - | CF Monterrey | 1:6 | |
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| 10. Ronde | 07.03.2021 | Atlas Guadalajara | - | FC Juárez | 2:0 | |
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| 11. Ronde | 13.03.2021 | FC Juárez | - | Pumas UNAM | 1:1 | |
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| 12. Ronde | 20.03.2021 | Club Necaxa | - | FC Juárez | 1:0 | ||||
| 13. Ronde | 03.04.2021 | FC Juárez | - | Cruz Azul | 0:1 |
Ecuador