| 1. Ronde | 24.07.2021 | CF Monterrey [U16] | - | Santos Laguna [U16] | 4:4 | ||||
| 3. Ronde | 07.08.2021 | Santos Laguna [U16] | - | UANL Tigres [U16] | 3:1 | ||||
| 7. Ronde | 04.09.2021 | Santos Laguna [U16] | - | Club León [U16] | 1:0 | ||||
| 17. Ronde | 13.11.2021 | Santos Laguna [U16] | - | Deportivo Guadalajara [U16] | 0:1 |
Mexico