| 1. Ronde | 03.08.2002 | Atlas Guadalajara | - | Santos Laguna | 1:2 | ||||
| 2. Ronde | 11.08.2002 | Santos Laguna | - | Gallos Blancos (old) | 0:0 |  |
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| 3. Ronde | 18.08.2002 | Puebla FC | - | Santos Laguna | 3:1 | ||||
| 4. Ronde | 25.08.2002 | Santos Laguna | - | CF América | 0:1 | ||||
| 5. Ronde | 31.08.2002 | Jaguares Chiapas | - | Santos Laguna | 2:0 | ||||
| 6. Ronde | 08.09.2002 | Santos Laguna | - | Cruz Azul | 1:3 | ||||
| 7. Ronde | 12.09.2002 | UAG Tecos | - | Santos Laguna | 2:1 |  |
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| 8. Ronde | 15.09.2002 | Santos Laguna | - | UANL Tigres | 3:1 | ||||
| 9. Ronde | 22.09.2002 | CF Pachuca | - | Santos Laguna | 0:0 | |
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| 10. Ronde | 28.09.2002 | Santos Laguna | - | Deportivo Guadalajara | 4:2 |  |
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| 12. Ronde | 13.10.2002 | Santos Laguna | - | Atletico Celaya | 2:0 | ||||
| 13. Ronde | 17.10.2002 | Santos Laguna | - | Club Necaxa | 3:2 | ||||
| 14. Ronde | 20.10.2002 | Atlante | - | Santos Laguna | 3:1 | ||||
| 15. Ronde | 27.10.2002 | Santos Laguna | - | Monarcas Morelia | 2:2 | |
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| 16. Ronde | 03.11.2002 | Pumas UNAM | - | Santos Laguna | 1:0 | ||||
| 17. Ronde | 10.11.2002 | Santos Laguna | - | Veracruz (old) | 4:2 | |
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| 18. Ronde | 16.11.2002 | CF Monterrey | - | Santos Laguna | 0:0 | ||||
| 19. Ronde | 24.11.2002 | Santos Laguna | - | Deportivo Toluca | 5:2 |
Mexico