| 1. Ronde | 18.01.2004 | Santos Laguna | - | Deportivo Guadalajara | 0:1 |  |
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| 2. Ronde | 25.01.2004 | Club Necaxa | - | Santos Laguna | 2:2 | ||||
| 3. Ronde | 01.02.2004 | Santos Laguna | - | Puebla FC | 2:0 | ||||
| 4. Ronde | 08.02.2004 | Pumas UNAM | - | Santos Laguna | 3:2 |  |
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| 6. Ronde | 21.02.2004 | Veracruz (old) | - | Santos Laguna | 2:1 | ||||
| 7. Ronde | 26.02.2004 | Santos Laguna | - | UAG Tecos | 2:1 | |
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| 8. Ronde | 29.02.2004 | CF Monterrey | - | Santos Laguna | 2:1 | ||||
| 10. Ronde | 14.03.2004 | Atlas Guadalajara | - | Santos Laguna | 2:0 | ||||
| 11. Ronde | 21.03.2004 | Santos Laguna | - | Real San Luis | 2:0 | |
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| 12. Ronde | 28.03.2004 | Club Irapuato | - | Santos Laguna | 0:3 | ||||
| 13. Ronde | 04.04.2004 | Atlante | - | Santos Laguna | 2:1 | ||||
| 14. Ronde | 11.04.2004 | Santos Laguna | - | Jaguares Chiapas | 1:1 | ||||
| 17. Ronde | 01.05.2004 | Gallos Blancos (old) | - | Santos Laguna | 2:0 | ||||
| 19. Ronde | 16.05.2004 | Deportivo Toluca | - | Santos Laguna | 4:1 |
Mexico