| 1. Ronde | 24.01.2016 | River Plate | - | Cerro Porteño | 0:2 | ||||
| 2. Ronde | 31.01.2016 | Sportivo Luqueño | - | Cerro Porteño | 2:1 |  |
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| 3. Ronde | 05.02.2016 | Cerro Porteño | - | General Caballero ZC | 3:0 | |
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| 4. Ronde | 08.02.2016 | Guaraní | - | Cerro Porteño | 0:0 | |
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| 5. Ronde | 13.02.2016 | Cerro Porteño | - | Club Rubio Ñu | 1:2 | ||||
| 6. Ronde | 21.02.2016 | Club Olimpia | - | Cerro Porteño | 0:1 | ||||
| 7. Ronde | 29.02.2016 | Cerro Porteño | - | Sol de América | 1:4 | |
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| 9. Ronde | 06.03.2016 | Cerro Porteño | - | Club Nacional | 1:2 | ||||
| 11. Ronde | 21.03.2016 | Cerro Porteño | - | General Díaz | 2:2 | ||||
| 12. Ronde | 01.04.2016 | Cerro Porteño | - | River Plate | 4:0 |  |
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| 13. Ronde | 05.04.2016 | Cerro Porteño | - | Sportivo Luqueño | 2:1 | ||||
| 14. Ronde | 10.04.2016 | General Caballero ZC | - | Cerro Porteño | 2:4 | ||||
| 15. Ronde | 18.04.2016 | Cerro Porteño | - | Guaraní | 3:4 | ||||
| 17. Ronde | 24.04.2016 | Cerro Porteño | - | Club Olimpia | 1:2 | ||||
| 18. Ronde | 01.05.2016 | Sol de América | - | Cerro Porteño | 2:2 |
Argentinië