| 1. Ronde | 10.01.2021 | Atlas Guadalajara | - | CF Monterrey | 0:2 | ||||
| 2. Ronde | 18.01.2021 | Gallos Blancos | - | Atlas Guadalajara | 1:0 | ||||
| 3. Ronde | 24.01.2021 | Atlas Guadalajara | - | UANL Tigres | 0:2 | ||||
| 5. Ronde | 07.02.2021 | Atlas Guadalajara | - | Santos Laguna | 1:1 |  |
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| 6. Ronde | 16.02.2021 | CF Pachuca | - | Atlas Guadalajara | 0:1 | ||||
| 8. Ronde | 28.02.2021 | Deportivo Toluca | - | Atlas Guadalajara | 0:0 | ||||
| 12. Ronde | 21.03.2021 | Cruz Azul | - | Atlas Guadalajara | 3:2 | ||||
| 14. Ronde | 11.04.2021 | Atlas Guadalajara | - | Club León | 1:3 | ||||
| 15. Ronde | 17.04.2021 | Mazatlán FC | - | Atlas Guadalajara | 0:0 | ||||
| 16. Ronde | 25.04.2021 | Atlas Guadalajara | - | Deportivo Guadalajara | 0:1 | ||||
| 17. Ronde | 01.05.2021 | Club Necaxa | - | Atlas Guadalajara | 1:5 | |
Mexico
Cuba