| 1. Ronde | 17.07.2021 | Unión de Santa Fe | - | Boca Juniors | 1:1 |  |
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| 5. Ronde | 08.08.2021 | Boca Juniors | - | Argentinos Juniors | 1:1 | |
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| 8. Ronde | 26.08.2021 | Platense | - | Boca Juniors | 1:3 | ||||
| 10. Ronde | 05.09.2021 | Rosario Central | - | Boca Juniors | 1:2 | |
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| 11. Ronde | 15.09.2021 | Boca Juniors | - | Defensa y Justicia | 0:0 | ||||
| 12. Ronde | 19.09.2021 | Atlético Tucumán | - | Boca Juniors | 1:2 | |
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| 14. Ronde | 03.10.2021 | River Plate | - | Boca Juniors | 2:1 | ||||
| 15. Ronde | 10.10.2021 | Boca Juniors | - | Lanús | 4:2 | |
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| 17. Ronde | 21.10.2021 | Boca Juniors | - | Godoy Cruz | 2:1 | ||||
| 18. Ronde | 25.10.2021 | Vélez Sarsfield | - | Boca Juniors | 2:0 | ||||
| 20. Ronde | 09.11.2021 | Aldosivi | - | Boca Juniors | 0:3 | ||||
| 21. Ronde | 20.11.2021 | Boca Juniors | - | Sarmiento de Junín | 2:0 | ||||
| 23. Ronde | 30.11.2021 | Boca Juniors | - | Newell's Old Boys | 0:0 | ||||
| 24. Ronde | 04.12.2021 | Arsenal de Sarandí | - | Boca Juniors | 1:1 |
Colombia
Argentinië