| 12. Ronde | 20.03.2021 | Atlético San Luis [U20] | - | Pumas UNAM [U20] | 2:1 | ||||
| 13. Ronde | 03.04.2021 | CF Monterrey [U20] | - | Atlético San Luis [U20] | 4:1 | ||||
| 14. Ronde | 09.04.2021 | FC Juárez [U20] | - | Atlético San Luis [U20] | 2:2 | ||||
| 16. Ronde | 24.04.2021 | Cruz Azul [U20] | - | Atlético San Luis [U20] | 0:1 | ||||
| 17. Ronde | 29.04.2021 | Atlético San Luis [U20] | - | CF Pachuca [U20] | 2:0 |
Mexico