| 1. Ronde | 08.01.2022 | FC Juárez | - | Club Necaxa | 2:1 |  |
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| 2. Ronde | 16.01.2022 | Cruz Azul | - | FC Juárez | 1:0 | |
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| 3. Ronde | 21.01.2022 | Atlético San Luis | - | FC Juárez | 0:1 | |
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| 4. Ronde | 10.02.2022 | FC Juárez | - | Deportivo Guadalajara | 1:3 | ||||
| 6. Ronde | 19.02.2022 | FC Juárez | - | Santos Laguna | 0:0 | |
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| 7. Ronde | 26.02.2022 | FC Juárez | - | UANL Tigres | 2:3 | ||||
| 8. Ronde | 02.03.2022 | Puebla FC | - | FC Juárez | 1:1 | ||||
| 9. Ronde | 05.03.2022 | FC Juárez | - | Club León | 0:1 | ||||
| 10. Ronde | 12.03.2022 | FC Juárez | - | Atlas Guadalajara | 1:2 | ||||
| 5. Ronde | 16.03.2022 | CF Monterrey | - | FC Juárez | 3:0 | ||||
| 11. Ronde | 21.03.2022 | Club Tijuana | - | FC Juárez | 1:0 | ||||
| 12. Ronde | 03.04.2022 | FC Juárez | - | Pumas UNAM | 0:1 | ||||
| 13. Ronde | 10.04.2022 | CF América | - | FC Juárez | 3:0 | ||||
| 14. Ronde | 16.04.2022 | FC Juárez | - | CF Pachuca | 1:2 | ||||
| 15. Ronde | 20.04.2022 | Deportivo Toluca | - | FC Juárez | 0:1 | ||||
| 16. Ronde | 23.04.2022 | FC Juárez | - | Mazatlán FC | 0:2 | |
Mexico