| 1. Ronde | 25.07.2021 | Club Tijuana [U18] | - | UANL Tigres [U18] | 1:0 |  |
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| 2. Ronde | 31.07.2021 | Club León [U18] | - | Club Tijuana [U18] | 2:1 | ||||
| 3. Ronde | 06.08.2021 | Club Tijuana [U18] | - | Deportivo Toluca [U18] | 3:0 | ||||
| 4. Ronde | 13.08.2021 | FC Juárez [U18] | - | Club Tijuana [U18] | 3:2 | |
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| 5. Ronde | 17.08.2021 | Club Tijuana [U18] | - | Puebla FC [U18] | 5:2 | ||||
| 6. Ronde | 22.08.2021 | CF América [U18] | - | Club Tijuana [U18] | 4:0 | ||||
| 7. Ronde | 27.08.2021 | Club Tijuana [U18] | - | CF Monterrey [U18] | 0:0 | ||||
| 8. Ronde | 10.09.2021 | Club Tijuana [U18] | - | Santos Laguna [U18] | 3:0 | ||||
| 9. Ronde | 16.09.2021 | Atlético San Luis [U18] | - | Club Tijuana [U18] | 1:0 | ||||
| 10. Ronde | 24.09.2021 | Club Tijuana [U18] | - | Mazatlán FC [U18] | 1:2 | ||||
| 11. Ronde | 28.09.2021 | Club Necaxa [U18] | - | Club Tijuana [U18] | 4:0 | ||||
| 14. Ronde | 20.10.2021 | Club Tijuana [U18] | - | Deportivo Guadalajara [U18] | 1:3 |
Mexico