| 2. Ronde | 15.01.2022 | Atlas Guadalajara [U20] | - | Atlético San Luis [U20] | 1:3 | ||||
| 3. Ronde | 20.01.2022 | Atlético San Luis [U20] | - | FC Juárez [U20] | 7:1 |  |
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| 6. Ronde | 19.02.2022 | UANL Tigres [U20] | - | Atlético San Luis [U20] | 1:1 |  |
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| 15. Ronde | 20.04.2022 | Atlético San Luis [U20] | - | Pumas UNAM [U20] | 2:1 |
Mexico