| 2. Ronde | 10.07.2022 | Club León [U18] | - | Pumas UNAM [U18] | 1:2 | ||||
| 3. Ronde | 17.07.2022 | Pumas UNAM [U18] | - | Club Necaxa [U18] | 2:3 | ||||
| 4. Ronde | 24.07.2022 | CF Pachuca [U18] | - | Pumas UNAM [U18] | 1:1 | ||||
| 5. Ronde | 27.07.2022 | Pumas UNAM [U18] | - | Mazatlán FC [U18] | 2:0 |  |
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| 6. Ronde | 30.07.2022 | Pumas UNAM [U18] | - | CF Monterrey [U18] | 2:1 | ||||
| 7. Ronde | 06.08.2022 | Puebla FC [U18] | - | Pumas UNAM [U18] | 1:0 | ||||
| 8. Ronde | 13.08.2022 | Pumas UNAM [U18] | - | CF América [U18] | 1:2 | ||||
| 9. Ronde | 18.08.2022 | Atlético San Luis [U18] | - | Pumas UNAM [U18] | 2:1 | ||||
| 10. Ronde | 21.08.2022 | Pumas UNAM [U18] | - | Santos Laguna [U18] | 2:0 |  |
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| 12. Ronde | 03.09.2022 | Atlas Guadalajara [U18] | - | Pumas UNAM [U18] | 1:1 | ||||
| 13. Ronde | 07.09.2022 | Pumas UNAM [U18] | - | Gallos Blancos [U18] | 1:0 | ||||
| 14. Ronde | 10.09.2022 | Deportivo Toluca [U18] | - | Pumas UNAM [U18] | 0:1 | ||||
| 17. Ronde | 30.09.2022 | FC Juárez [U18] | - | Pumas UNAM [U18] | 1:1 |
Mexico