| 1. Ronde | 26.07.2021 | Cruz Azul [U20] | - | Mazatlán FC [U20] | 1:1 | ||||
| 4. Ronde | 14.08.2021 | Club León [U20] | - | Mazatlán FC [U20] | 1:0 | ||||
| 5. Ronde | 17.08.2021 | Deportivo Toluca [U20] | - | Mazatlán FC [U20] | 3:1 | ||||
| 8. Ronde | 11.09.2021 | CF América [U20] | - | Mazatlán FC [U20] | 3:0 | ||||
| 10. Ronde | 25.09.2021 | Club Tijuana [U20] | - | Mazatlán FC [U20] | 3:5 | ||||
| 11. Ronde | 28.09.2021 | Mazatlán FC [U20] | - | FC Juárez [U20] | 2:2 | ||||
| 13. Ronde | 15.10.2021 | Mazatlán FC [U20] | - | Atlas Guadalajara [U20] | 3:1 |  |
Mexico