| 1. Ronde | 03.07.2022 | Atlético San Luis [U20] | - | Club León [U20] | 1:3 | ||||
| 2. Ronde | 10.07.2022 | Club León [U20] | - | Pumas UNAM [U20] | 3:2 | ||||
| 3. Ronde | 15.07.2022 | Puebla FC [U20] | - | Club León [U20] | 3:1 |  |
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| 4. Ronde | 20.07.2022 | Deportivo Guadalajara [U20] | - | Club León [U20] | 1:3 | ||||
| 5. Ronde | 26.07.2022 | Club León [U20] | - | Deportivo Toluca [U20] | 0:0 | ||||
| 6. Ronde | 31.07.2022 | Club León [U20] | - | CF América [U20] | 1:0 | ||||
| 7. Ronde | 06.08.2022 | CF Monterrey [U20] | - | Club León [U20] | 2:0 | ||||
| 9. Ronde | 18.08.2022 | Santos Laguna [U20] | - | Club León [U20] | 2:3 | ||||
| 11. Ronde | 28.08.2022 | Club León [U20] | - | Atlas Guadalajara [U20] | 0:1 | |
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| 12. Ronde | 02.09.2022 | Club Necaxa [U20] | - | Club León [U20] | 2:2 | ||||
| 13. Ronde | 06.09.2022 | Club León [U20] | - | FC Juárez [U20] | 3:1 | |
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| 14. Ronde | 10.09.2022 | UANL Tigres [U20] | - | Club León [U20] | 3:2 | ||||
| 16. Ronde | 15.09.2022 | Cruz Azul [U20] | - | Club León [U20] | 1:1 | ||||
| 15. Ronde | 18.09.2022 | Club León [U20] | - | Gallos Blancos [U20] | 3:2 | ||||
| 8. Ronde | 27.09.2022 | Club León [U20] | - | Mazatlán FC [U20] | 4:1 |  |
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| 17. Ronde | 02.10.2022 | Club León [U20] | - | Club Tijuana [U20] | 1:0 | |
Mexico