| 3. Ronde | 20.01.2023 | Mazatlán FC [U18] | - | Santos Laguna [U18] | 0:2 | ||||
| 4. Ronde | 26.01.2023 | Atlas Guadalajara [U18] | - | Santos Laguna [U18] | 1:0 | ||||
| 6. Ronde | 10.02.2023 | FC Juárez [U18] | - | Santos Laguna [U18] | 3:3 | ||||
| 8. Ronde | 18.02.2023 | Atlético San Luis [U18] | - | Santos Laguna [U18] | 3:4 | ||||
| 11. Ronde | 12.03.2023 | Santos Laguna [U18] | - | Club Tijuana [U18] | 3:0 | ||||
| 12. Ronde | 19.03.2023 | Club León [U18] | - | Santos Laguna [U18] | 4:1 | ||||
| 13. Ronde | 31.03.2023 | Club Necaxa [U18] | - | Santos Laguna [U18] | 4:1 | ||||
| 14. Ronde | 09.04.2023 | Santos Laguna [U18] | - | CF Pachuca [U18] | 2:0 | ||||
| 17. Ronde | 29.04.2023 | Cruz Azul [U18] | - | Santos Laguna [U18] | 2:0 |
Mexico