| 1. Ronde | 27.07.2008 | UANL Tigres | - | CF Pachuca | 0:0 | ||||
| 2. Ronde | 03.08.2008 | CF Pachuca | - | Club San Luis | 2:3 | ||||
| 3. Ronde | 10.08.2008 | Atlante | - | CF Pachuca | 2:1 |  |
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| 4. Ronde | 17.08.2008 | CF Pachuca | - | CF América | 1:1 | ||||
| 5. Ronde | 24.08.2008 | Pumas UNAM | - | CF Pachuca | 3:1 | ||||
| 6. Ronde | 28.08.2008 | CF Pachuca | - | Puebla FC | 2:0 | ||||
| 7. Ronde | 31.08.2008 | Indios Juárez | - | CF Pachuca | 2:1 | ||||
| 8. Ronde | 14.09.2008 | CF Pachuca | - | Deportivo Guadalajara | 5:2 | ||||
| 10. Ronde | 28.09.2008 | CF Pachuca | - | CF Monterrey | 2:1 |  |
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| 11. Ronde | 05.10.2008 | Club Necaxa | - | CF Pachuca | 1:1 | ||||
| 12. Ronde | 12.10.2008 | CF Pachuca | - | Santos Laguna | 2:0 | |
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| 13. Ronde | 19.10.2008 | Deportivo Toluca | - | CF Pachuca | 3:0 | |
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| 15. Ronde | 02.11.2008 | Cruz Azul | - | CF Pachuca | 1:2 | ||||
| 9. Ronde | 06.11.2008 | UAG Tecos | - | CF Pachuca | 2:2 | ||||
| 16. Ronde | 09.11.2008 | Jaguares Chiapas | - | CF Pachuca | 2:1 | ||||
| 17. Ronde | 16.11.2008 | CF Pachuca | - | Atlas Guadalajara | 1:1 |
Mexico