| 6. Ronde | 12.02.2022 | Club León [U16] | - | Atlético San Luis [U16] | 2:1 | ||||
| 8. Ronde | 26.02.2022 | Atlas Guadalajara [U16] | - | Club León [U16] | 5:0 | ||||
| 9. Ronde | 05.03.2022 | Club León [U16] | - | Mazatlán FC [U16] | 4:0 | ||||
| 14. Ronde | 09.04.2022 | Club León [U16] | - | Atlas Guadalajara [U16] | 0:2 | ||||
| 15. Ronde | 16.04.2022 | Atlético San Luis [U16] | - | Club León [U16] | 1:3 | ||||
| 16. Ronde | 23.04.2022 | Club León [U16] | - | Club Tijuana [U16] | 1:0 | ||||
| 17. Ronde | 30.04.2022 | Club León [U16] | - | CF Monterrey [U16] | 1:2 | ||||
| 18. Ronde | 07.05.2022 | Santos Laguna [U16] | - | Club León [U16] | 2:1 |  |
Mexico