| 3. Ronde | 01.09.2021 | Académica de Coimbra [A-jun] | - | CD Nacional [A-jun] | 2:0 | ||||
| 5. Ronde | 11.09.2021 | GD Estoril [A-jun] | - | CD Nacional [A-jun] | 1:1 | ||||
| 8. Ronde | 03.10.2021 | CD Nacional [A-jun] | - | FC Alverca [A-jun] | 3:1 | ||||
| 2. Ronde | 09.10.2021 | CD Nacional [A-jun] | - | UD Vilafranquense [A-jun] | 1:1 | ||||
| 9. Ronde | 16.10.2021 | Amora FC [A-jun] | - | CD Nacional [A-jun] | 1:1 | ||||
| 10. Ronde | 23.10.2021 | União Leiria [A-jun] | - | CD Nacional [A-jun] | 1:0 | ||||
| 4. Ronde | 27.10.2021 | CD Nacional [A-jun] | - | SG Sacavenense [A-jun] | 2:1 | ||||
| 16. Ronde | 04.12.2021 | CD Nacional [A-jun] | - | GD Estoril [A-jun] | 0:0 | ||||
| 7. Ronde | 18.12.2021 | Sporting CP [A-jun] | - | CD Nacional [A-jun] | 1:1 | ||||
| 14. Ronde | 11.01.2022 | CD Nacional [A-jun] | - | Académica de Coimbra [A-jun] | 3:2 | ||||
| 20. Ronde | 15.01.2022 | CD Nacional [A-jun] | - | Amora FC [A-jun] | 0:1 | ||||
| 21. Ronde | 22.01.2022 | CD Nacional [A-jun] | - | União Leiria [A-jun] | 1:0 | ||||
| 22. Ronde | 29.01.2022 | SL Benfica [A-jun] | - | CD Nacional [A-jun] | 4:0 |
Portugal