| 2. Ronde | 16.01.2021 | Deportivo Guadalajara [U20] | - | Deportivo Toluca [U20] | 5:3 | ||||
| 3. Ronde | 21.01.2021 | Atlético San Luis [U20] | - | Deportivo Guadalajara [U20] | 3:2 | ||||
| 12. Ronde | 20.03.2021 | CF Monterrey [U20] | - | Deportivo Guadalajara [U20] | 1:0 | ||||
| 1. Ronde | 27.03.2021 | Puebla FC [U20] | - | Deportivo Guadalajara [U20] | 2:4 |  |
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| 13. Ronde | 04.04.2021 | Deportivo Guadalajara [U20] | - | Santos Laguna [U20] | 5:2 | ||||
| 14. Ronde | 10.04.2021 | Cruz Azul [U20] | - | Deportivo Guadalajara [U20] | 0:1 |
Mexico