| 6. Ronde | 11.09.2021 | SC YF/Juventus Zürich | - | SC Cham | 4:2 | ||||
| 8. Ronde | 25.09.2021 | SC Cham | - | FC Black Stars Basel | 2:1 |  |
|||
| 9. Ronde | 02.10.2021 | FC Bavois | - | SC Cham | 1:4 | |
|||
| 10. Ronde | 09.10.2021 | SC Cham | - | FC Stade Nyonnais | 1:3 | ||||
| 11. Ronde | 16.10.2021 | AC Bellinzona | - | SC Cham | 2:1 | ||||
| 12. Ronde | 23.10.2021 | SC Cham | - | BSC Young Boys II | 1:3 | ||||
| 13. Ronde | 31.10.2021 | FC Chiasso | - | SC Cham | 3:0 | ||||
| 14. Ronde | 06.11.2021 | SC Cham | - | FC Biel/Bienne | 2:2 | ||||
| 15. Ronde | 13.11.2021 | FC Basel 1893 II | - | SC Cham | 3:4 | ||||
| 16. Ronde | 20.11.2021 | FC Sion II | - | SC Cham | 3:4 | ||||
| 17. Ronde | 27.11.2021 | SC Cham | - | Etoile Carouge FC | 1:0 | ||||
| 18. Ronde | 04.12.2021 | FC Zürich II | - | SC Cham | 3:1 | ||||
| 19. Ronde | 19.02.2022 | SC Cham | - | FC Breitenrain Bern | 0:0 | ||||
| 20. Ronde | 26.02.2022 | SC Brühl | - | SC Cham | 2:2 | ||||
| 21. Ronde | 05.03.2022 | SC Cham | - | SC YF/Juventus Zürich | 1:0 |
Zwitserland