| 3. Ronde | 08.08.2020 | CF Monterrey [U20] | - | Santos Laguna [U20] | 2:1 | ||||
| 4. Ronde | 13.08.2020 | CF América [U20] | - | Santos Laguna [U20] | 4:0 | ||||
| 5. Ronde | 16.08.2020 | Santos Laguna [U20] | - | Atlas Guadalajara [U20] | 0:2 |  |
|||
| 1. Ronde | 10.10.2020 | Cruz Azul [U20] | - | Santos Laguna [U20] | 2:1 | |
|||
| 14. Ronde | 18.10.2020 | Santos Laguna [U20] | - | CF Pachuca [U20] | 1:2 | ||||
| 15. Ronde | 25.10.2020 | Santos Laguna [U20] | - | Atlético San Luis [U20] | 2:1 | ||||
| 16. Ronde | 02.11.2020 | Club León [U20] | - | Santos Laguna [U20] | 4:3 | ||||
| 2. Ronde | 13.11.2020 | Santos Laguna [U20] | - | Deportivo Guadalajara [U20] | 2:2 |
Mexico