| 3. Ronde | 11.09.2021 | Mosta FC | - | Hamrun Spartans | 1:2 | ||||
| 4. Ronde | 18.09.2021 | Hibernians FC | - | Mosta FC | 3:2 | ||||
| 5. Ronde | 26.09.2021 | Mosta FC | - | Balzan FC | 2:1 | ||||
| 6. Ronde | 17.10.2021 | St. Luċija FC | - | Mosta FC | 2:2 | ||||
| 7. Ronde | 23.10.2021 | Mosta FC | - | Floriana FC | 1:1 |  |
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| 8. Ronde | 31.10.2021 | Sliema Wanderers | - | Mosta FC | 2:3 | ||||
| 9. Ronde | 20.11.2021 | Mosta FC | - | Gżira United | 2:2 | |
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| 10. Ronde | 27.11.2021 | Valletta FC | - | Mosta FC | 3:1 | ||||
| 11. Ronde | 04.12.2021 | Mosta FC | - | Gudja United | 0:3 |
Oostenrijk
Kosovo