| 1. Ronde | 22.08.2021 | HSC'21 | - | EVV | 0:1 | ||||
| 2. Ronde | 29.08.2021 | OFC | - | HSC'21 | 2:1 | ||||
| 5. Ronde | 19.09.2021 | Dongen | - | HSC'21 | 1:1 | ||||
| 6. Ronde | 26.09.2021 | HSC'21 | - | HVV Hollandia | 2:2 |  |
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| 8. Ronde | 10.10.2021 | HSC'21 | - | Hoogland | 4:1 | ||||
| 9. Ronde | 17.10.2021 | DEM | - | HSC'21 | 0:3 | ||||
| 10. Ronde | 24.10.2021 | HSC'21 | - | Blauw Geel '38 | 4:2 | ||||
| 11. Ronde | 07.11.2021 | GVV Unitas | - | HSC'21 | 1:0 | ||||
| 14. Ronde | 28.11.2021 | HSC'21 | - | OSS '20 | 4:0 | ||||
| 16. Ronde | 27.02.2022 | HSC'21 | - | ADO '20 | 3:1 | ||||
| 22. Ronde | 06.04.2022 | HSC'21 | - | OFC | 1:1 | ||||
| 24. Ronde | 10.04.2022 | Blauw Geel '38 | - | HSC'21 | 2:0 | ||||
| 19. Ronde | 13.04.2022 | HVV Hollandia | - | HSC'21 | 0:4 | ||||
| 25. Ronde | 16.04.2022 | HSC'21 | - | DEM | 1:0 | ||||
| 26. Ronde | 18.04.2022 | Hoogland | - | HSC'21 | 0:1 | |
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| 27. Ronde | 24.04.2022 | HSC'21 | - | Gemert | 3:2 |  |
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| 28. Ronde | 01.05.2022 | EVV | - | HSC'21 | 1:4 | |
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| 29. Ronde | 08.05.2022 | Groene Ster | - | HSC'21 | 0:3 | |
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| 30. Ronde | 15.05.2022 | HSC'21 | - | Quick | 3:3 | |
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| 31. Ronde | 22.05.2022 | ADO '20 | - | HSC'21 | 4:1 | |
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| 32. Ronde | 26.05.2022 | HSC'21 | - | UNA | 7:2 | |
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| 33. Ronde | 29.05.2022 | OSS '20 | - | HSC'21 | 3:0 | ||||
| 34. Ronde | 06.06.2022 | HSC'21 | - | Westlandia | 2:1 |
Nederland