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| 10.10.2021 | 14:00 | ADO '20 | - | Westlandia | 3:0 (1:0) | |
| 14:00 | Dongen | - | Blauw Geel '38 | 2:1 (0:0) | ||
| 14:00 | HVV Hollandia | - | Groene Ster | 3:0 (1:0) | ||
| 14:00 | JOS Watergraafsmeer | - | OSS '20 | 3:3 (2:2) | ||
| 14:00 | Gemert | - | Hercules | 2:2 (0:1) | ||
| 14:30 | HSC'21 | - | Hoogland | 4:1 (1:0) | ||
| 14:30 | EVV | - | Quick | 1:0 (0:0) | ||
| 14:30 | OFC | - | DEM | 3:1 (0:1) | ||
| 14:30 | UNA | - | GVV Unitas | 3:2 (1:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
OFC | 8 | 6 | 1 | 1 | 17:8 | 9 | 19 |
| 2 |
|
GVV Unitas | 8 | 5 | 1 | 2 | 16:11 | 5 | 16 |
| 3 |
|
OSS '20 | 8 | 5 | 1 | 2 | 17:11 | 6 | 15 |
| 4 |
|
UNA | 8 | 5 | 0 | 3 | 17:15 | 2 | 15 |
| 5 |
|
Hercules | 8 | 4 | 2 | 2 | 17:11 | 6 | 14 |
| 6 |
|
Gemert | 8 | 3 | 5 | 0 | 15:10 | 5 | 14 |
| 7 |
|
ADO '20 | 8 | 4 | 0 | 4 | 16:13 | 3 | 12 |
| 8 |
|
Groene Ster | 8 | 3 | 2 | 3 | 13:15 | -2 | 11 |
| 9 |
|
Quick | 8 | 3 | 1 | 4 | 7:7 | 0 | 10 |
| 10 |
|
EVV | 8 | 2 | 4 | 2 | 6:7 | -1 | 10 |
| 11 |
|
Blauw Geel '38 | 8 | 3 | 1 | 4 | 10:14 | -4 | 10 |
| 12 |
|
JOS Watergraafsmeer | 8 | 3 | 2 | 3 | 14:13 | 1 | 9 |
| 13 |
|
Westlandia | 8 | 2 | 3 | 3 | 12:11 | 1 | 9 |
| 14 |
|
Dongen | 8 | 2 | 3 | 3 | 11:11 | 0 | 9 |
| 15 |
|
HVV Hollandia | 8 | 2 | 3 | 3 | 8:9 | -1 | 9 |
| 16 |
|
Hoogland | 8 | 1 | 3 | 4 | 7:18 | -11 | 6 |
| 17 |
|
HSC'21 | 8 | 1 | 2 | 5 | 10:16 | -6 | 5 |
| 18 |
|
DEM | 8 | 0 | 2 | 6 | 3:16 | -13 | 2 |
| Promotie | |
| Promotie en degradatie | |
| Degradatie |
