| 4. Ronde | 28.08.2021 | SC Brühl | - | SC YF/Juventus Zürich | 2:5 | ||||
| 5. Ronde | 04.09.2021 | SC Cham | - | SC Brühl | 0:1 | ||||
| 6. Ronde | 11.09.2021 | SC Brühl | - | FC Black Stars Basel | 1:3 | ||||
| 7. Ronde | 18.09.2021 | FC Bavois | - | SC Brühl | 1:3 | ||||
| 8. Ronde | 25.09.2021 | SC Brühl | - | FC Stade Nyonnais | 2:5 | ||||
| 9. Ronde | 02.10.2021 | AC Bellinzona | - | SC Brühl | 2:1 | ||||
| 12. Ronde | 23.10.2021 | SC Brühl | - | FC Biel/Bienne | 1:1 | ||||
| 13. Ronde | 30.10.2021 | FC Basel 1893 II | - | SC Brühl | 1:3 | ||||
| 14. Ronde | 06.11.2021 | SC Brühl | - | FC Sion II | 0:1 | ||||
| 15. Ronde | 13.11.2021 | Etoile Carouge FC | - | SC Brühl | 2:1 |  |
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| 16. Ronde | 20.11.2021 | FC Zürich II | - | SC Brühl | 0:0 | ||||
| 17. Ronde | 27.11.2021 | SC Brühl | - | FC Breitenrain Bern | 1:3 | ||||
| 18. Ronde | 04.12.2021 | FC Rapperswil-Jona | - | SC Brühl | 2:1 |
Zwitserland
Italië