| 1. Ronde | 26.07.2020 | Deportivo Guadalajara | - | Club León | 0:0 | ||||
| 3. Ronde | 09.08.2020 | Cruz Azul | - | Club León | 2:0 | ||||
| 4. Ronde | 12.08.2020 | CF Pachuca | - | Club León | 0:1 | ||||
| 5. Ronde | 18.08.2020 | Club León | - | Club Tijuana | 2:1 | ||||
| 6. Ronde | 22.08.2020 | FC Juárez | - | Club León | 0:0 | ||||
| 7. Ronde | 01.09.2020 | Club León | - | Atlas Guadalajara | 2:1 | ||||
| 9. Ronde | 10.09.2020 | Club León | - | UANL Tigres | 1:1 | ||||
| 12. Ronde | 28.09.2020 | Atlético San Luis | - | Club León | 0:2 | ||||
| 14. Ronde | 20.10.2020 | Club León | - | CF América | 3:2 | ||||
| 15. Ronde | 24.10.2020 | Puebla FC | - | Club León | 1:2 | ||||
| 16. Ronde | 03.11.2020 | Club León | - | Santos Laguna | 2:1 | ||||
| 17. Ronde | 08.11.2020 | Deportivo Toluca | - | Club León | 2:2 |  |
Mexico