| 1. Ronde | 09.01.2021 | CF América [U20] | - | Atlético San Luis [U20] | 4:1 |  |
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| 2. Ronde | 15.01.2021 | Club Necaxa [U20] | - | Atlético San Luis [U20] | 2:1 | ||||
| 10. Ronde | 05.03.2021 | Atlético San Luis [U20] | - | Deportivo Toluca [U20] | 1:2 | ||||
| 11. Ronde | 14.03.2021 | Gallos Blancos [U20] | - | Atlético San Luis [U20] | 0:1 | |
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| 12. Ronde | 20.03.2021 | Atlético San Luis [U20] | - | Pumas UNAM [U20] | 2:1 | ||||
| 4. Ronde | 26.03.2021 | Club León [U20] | - | Atlético San Luis [U20] | 4:2 |  |
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| 13. Ronde | 03.04.2021 | CF Monterrey [U20] | - | Atlético San Luis [U20] | 4:1 | |
Mexico