| 3. Ronde | 21.01.2022 | Puebla FC [U18] | - | Club Tijuana [U18] | 1:1 | ||||
| 4. Ronde | 05.02.2022 | Club Tijuana [U18] | - | Pumas UNAM [U18] | 2:0 | ||||
| 7. Ronde | 25.02.2022 | Club Tijuana [U18] | - | Atlas Guadalajara [U18] | 3:3 | ||||
| 8. Ronde | 01.03.2022 | Deportivo Toluca [U18] | - | Club Tijuana [U18] | 1:1 | ||||
| 12. Ronde | 03.04.2022 | UANL Tigres [U18] | - | Club Tijuana [U18] | 2:0 | ||||
| 13. Ronde | 11.04.2022 | CF Pachuca [U18] | - | Club Tijuana [U18] | 1:2 |
Mexico