| 1. Ronde | 03.07.2022 | CF América | - | Atlas Guadalajara | 0:0 | ||||
| 2. Ronde | 10.07.2022 | CF Monterrey | - | CF América | 3:2 | ||||
| 6. Ronde | 01.08.2022 | Club León | - | CF América | 3:2 | ||||
| 7. Ronde | 08.08.2022 | CF América | - | FC Juárez | 2:1 | ||||
| 8. Ronde | 14.08.2022 | Pumas UNAM | - | CF América | 0:3 | ||||
| 10. Ronde | 21.08.2022 | CF América | - | Cruz Azul | 7:0 | ||||
| 16. Ronde | 24.08.2022 | Gallos Blancos | - | CF América | 0:1 | ||||
| 11. Ronde | 27.08.2022 | Mazatlán FC | - | CF América | 1:3 |  |
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| 12. Ronde | 04.09.2022 | CF América | - | UANL Tigres | 2:1 | ||||
| 13. Ronde | 07.09.2022 | CF América | - | Atlético San Luis | 3:0 | ||||
| 5. Ronde | 15.09.2022 | CF América | - | Santos Laguna | 3:3 | ||||
| 15. Ronde | 18.09.2022 | CF América | - | Deportivo Guadalajara | 2:1 |
Uruguay
Spanje