| 1. Ronde | 13.02.2022 | Rio Ave FC [A-jun] | - | GD Estoril [A-jun] | 0:1 | ||||
| 2. Ronde | 19.02.2022 | FC Alverca [A-jun] | - | Rio Ave FC [A-jun] | 1:0 | ||||
| 3. Ronde | 26.02.2022 | Rio Ave FC [A-jun] | - | Sporting Braga [A-jun] | 0:1 | ||||
| 4. Ronde | 05.03.2022 | FC Porto [A-jun] | - | Rio Ave FC [A-jun] | 1:1 | ||||
| 5. Ronde | 13.03.2022 | Rio Ave FC [A-jun] | - | SL Benfica [A-jun] | 3:3 |  |
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| 6. Ronde | 02.04.2022 | Sporting CP [A-jun] | - | Rio Ave FC [A-jun] | 3:1 | ||||
| 7. Ronde | 09.04.2022 | Rio Ave FC [A-jun] | - | Vitória Guimarães [A-jun] | 3:3 |
Portugal