| 2. Ronde | 19.02.2022 | Vitória Setúbal [A-jun] | - | UD Vilafranquense [A-jun] | 2:2 | ||||
| 3. Ronde | 26.02.2022 | Vitória Setúbal [A-jun] | - | Amora FC [A-jun] | 1:0 |  |
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| 4. Ronde | 05.03.2022 | União Leiria [A-jun] | - | Vitória Setúbal [A-jun] | 2:2 | ||||
| 6. Ronde | 19.03.2022 | Académica de Coimbra [A-jun] | - | Vitória Setúbal [A-jun] | 1:0 | ||||
| 9. Ronde | 16.04.2022 | UD Vilafranquense [A-jun] | - | Vitória Setúbal [A-jun] | 2:0 |
Portugal